0550 Positive Airway Pressure for Obstructive Sleep Apnea in Diastolic Heart Failure Patients Reduces Healthcare Resource Utilization

Abstract Introduction Although diastolic heart failure (HFpEF) patients frequently have comorbid obstructive sleep apnea (OSA), which has been associated with poor prognosis, the impact of positive airway pressure (PAP) therapy remains unclear. This retrospective study sought to investigate association between 1 year adherence PAP and healthcare resource utilization (HCRU) in newly diagnosed OSA HFpEF. Methods A national sample administrative claims data linked objective usage was used for this analysis. Eligible either had two encounters or one hospitalization a ICD-10 diagnosis code prior being initiated on therapy. HCRU measured as composite outcome hospitalizations emergency room (ER) visits. Propensity score matching create well-balanced groups differing levels assess outcomes. Risk-adjusted models were generate number needed treat (NNT) that referred need become adherent from non-adherent avoid visit. Results 4,237 HFpEF included. With propensity matching, 963 remained. After therapy, fewer visits than (1.16 per subject vs. 1.75, p < 0.001), driven by 57% reduction 36% ER patients. Total costs lower ($12,732 $15,610, p< 0.01). Converting patient would 1.25 (either visit hospitalization), an NNT 0.8. Conclusion are not adherent. More importantly, patients, highlighting clinical economic benefits treating Support (if any) Funding Source: ResMed